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Future transplant methodology is likely to place greater priority on stem cells and/or cultured cell lines as the tissue source, probably in closer conjunction with growth factors and other cell-activating substances

applied untargeted metabolomics (GC-MS and LC-MS) to plasma from ATTRV30M patients, identifying reduced tryptophan, phenylalanine, and tyrosine, along with altered malic acid and acylcarnitines (Table 3)

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Importantly, the weight loss trajectory showed continued progress throughout the study period, suggesting that longer treatment durations might yield even greater effects